Estriol 0.3% + Hyaluronic Acid 0.5% Face Cream
Read this leaflet carefully before using Estriol 0.3% + Hyaluronic Acid 0.5% face cream. This information is for patients who have been prescribed this treatment by a clinician following an online consultation.
What is Estriol 0.3% + Hyaluronic Acid 0.5% face cream and what is it used for?
Estriol 0.3% + Hyaluronic Acid 0.5% face cream is a prescription skincare treatment for facial skin changes associated with perimenopause and menopause. It may be prescribed for patients experiencing dryness, dullness, reduced firmness, reduced elasticity, or fine lines linked to hormonal skin changes.
Estriol is a form of oestrogen. Oestrogen levels naturally decline during perimenopause and menopause, and this can affect the skin barrier, hydration, collagen, elasticity, and overall skin texture.
Hyaluronic Acid is a hydrating ingredient that helps attract and hold water in the skin. It is included to support skin hydration and a smoother, more comfortable skin feel.
This cream is for facial use only. It is not intended to treat hot flushes, night sweats, vaginal dryness, or other symptoms of menopause. Speak to your clinician if you need advice about wider menopause symptoms or hormone replacement therapy.
What you need to know before using this treatment
- You are pregnant, breastfeeding, or planning a pregnancy.
- You have, or have previously had, breast cancer, womb cancer, or another hormone-sensitive cancer.
- You have unexplained vaginal bleeding.
- You have untreated thickening of the womb lining, also known as endometrial hyperplasia.
- You have ever had a blood clot in a vein, such as deep vein thrombosis or pulmonary embolism.
- You have ever had a stroke, heart attack, or serious circulation problem.
- You have active liver disease or have been told your liver tests are abnormal.
- You are allergic to estriol, hyaluronic acid, or any other ingredient in the cream.
- You have broken, infected, severely irritated, or inflamed skin on the area you intend to treat.
If any of these apply to you now or have applied in the past, get advice from your doctor, prescriber, or pharmacist before using this treatment.
Warnings and precautions
- Use only on facial skin as directed by your prescriber.
- Avoid contact with the eyes, eyelids, lips, mouth, nostrils, and mucous membranes.
- Do not apply to broken, infected, sunburnt, or severely irritated skin.
- Wash your hands after applying the cream.
- Do not share this treatment with anyone else, even if they have similar skin concerns.
- Stop using the cream and seek advice if you develop a rash, swelling, severe irritation, or signs of allergy.
- Seek medical advice urgently if you develop unexplained vaginal bleeding, breast changes, chest pain, shortness of breath, severe headache, leg swelling, or sudden weakness.
Menopausal skin can feel drier and more sensitive. Use a broad-spectrum sunscreen during the day and avoid excessive sun exposure, especially if you are using other active skincare products.
Other medicines and skincare products
Tell your prescriber or pharmacist if you are using, have recently used, or might use any other medicines or hormone treatments, including HRT, vaginal oestrogen, contraceptive hormones, or other prescribed skincare.
If you use strong active skincare ingredients such as retinoids, exfoliating acids, benzoyl peroxide, vitamin C, or prescription acne treatments, introduce this cream carefully and avoid applying too many active products at the same time unless advised.
Driving and using machines
This treatment is unlikely to affect your ability to drive or operate machines.
How to use Estriol 0.3% + Hyaluronic Acid 0.5% face cream
Always use this treatment exactly as your prescriber has told you. Check your dispensing label for the dose and frequency. If you are unsure, ask your prescriber or pharmacist.
Apply to clean, dry skin unless your prescriber has advised otherwise.
Apply a thin layer to the face. Avoid the eyelids, lips, nostrils, and broken skin.
Most patients are advised to use it once daily, usually in the evening, but follow your label.
Wash your hands after application to avoid accidental transfer to the eyes or other areas.
When to expect changes
Improvements in dryness and skin comfort may be noticed earlier, but changes in firmness, elasticity, texture, and fine lines usually take consistent use over several weeks to months.
If irritation occurs
If your skin becomes dry, red, stinging, or irritated, reduce the frequency of application and use a simple moisturiser. If symptoms persist or become severe, stop using the cream and contact your prescriber or pharmacist.
If too much is used
If you accidentally apply too much, remove the excess and continue as normal at the next application. Do not apply extra to make up for missed applications.
If you forget to apply it
Carry on as normal with your next scheduled application. Do not apply a double amount to make up for the missed dose.
If swallowed accidentally
If anyone, including a child, swallows the cream, seek medical advice immediately and take the container with you if possible.
Possible side effects
Like all medicines and skincare treatments, Estriol 0.3% + Hyaluronic Acid 0.5% face cream can cause side effects, although not everyone gets them.
Skin-related side effects
- Redness
- Dryness
- Stinging or burning sensation
- Itching
- Rash
- Temporary worsening of sensitivity
- Breakouts or blocked pores
- Contact dermatitis or allergic reaction
Hormone-related side effects
Although this is a topical facial treatment, estriol is an oestrogen. Contact your prescriber or pharmacist if you notice symptoms such as:
- Breast tenderness or breast changes
- Headache
- Nausea
- Mood changes
- Unexpected vaginal bleeding or spotting
- New pelvic pain or unusual discharge
You develop chest pain, shortness of breath, coughing blood, sudden leg swelling, severe headache, vision changes, weakness on one side of the body, or any signs of a serious allergic reaction such as swelling of the face, lips, tongue, or throat.
If you experience side effects, speak to your doctor, prescriber, or pharmacist. You can also report side effects through the MHRA Yellow Card Scheme at www.mhra.gov.uk/yellowcard or by searching for MHRA Yellow Card in the Google Play or Apple App Store.
How to store this treatment
- Keep out of the sight and reach of children.
- Store as directed on the dispensing label.
- Do not use after the expiry date shown on the dispensing label.
- Keep the container tightly closed when not in use.
- Protect from excessive heat and direct sunlight.
- Do not dispose of medicines via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required.
Contents of the cream and other information
The active ingredients are Estriol 0.3% and Hyaluronic Acid 0.5%.
Other ingredients
Other ingredients may vary depending on the formulation prescribed and dispensed. Please refer to your dispensing label and product packaging, or contact the pharmacy if you need a full excipient list.
What the treatment looks like
Estriol 0.3% + Hyaluronic Acid 0.5% face cream is usually supplied as a topical cream in an airless pump or suitable dispensing container. The appearance may vary slightly depending on the formulation.
Compounding Chemist contact information
HUB 30, LondonEast Business & Technical Park, Yew Tree Avenue, Dagenham, RM10 7FN
Telephone: +44 (0) 2037732729
Email: info@cchemist.com
Website: www.cchemist.com